Zelissen PM, Bast EJ, Croughs RJ (1995) Associated autoimmunity in Addison's disease. Irvine WJ, Barnes EW (1972) Adrenocortical insufficiency. In conclusion, in this review all the known pathogenic mechanisms causing disorders of nephrological interest in adrenal insufficiency are discussed.Īddison T (1855) On the constitutional and local effects of disease of the suprarenal capsules. In a peculiar way, these alterations were not controlled with repolarizing solutions, fluid replacement and increased volemia, but only after steroid administration. The blood tests showed in all three patients severe electrolyte disorders and acute renal failure which will be discussed in their physiopathogenetic mechanisms. Moreover, the fact that in a short time range we have diagnosed the three cases described as a guide in this review, has aroused our attention as nephrologists on a disease in which we have probably already encountered but without recognizing it. Many typical signs and symptoms, such as hyponatremia, hyperkalaemia, or renal insufficiency can represent the reasons for a nephrology consultation, especially in conditions of urgency, and they can easily be confused with other causes. Nowadays, the causes of adrenal insufficiency are autoimmune disease for 70–90% and tuberculosis for 7–20%. Addison disease is due to the destruction or dysfunction of the entire adrenal cortex.
0 kommentar(er)
